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comN [2018-01-05 10:06:32]
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comN [2018-01-05 10:06:32]

mediates post-transcriptional control of comE operon expression
locus
BSU27660
pI
4.62
mw
11.45 kDa
protein length
98 aa Sequence Blast
gene length
294 bp Sequence Blast
function
regulation of competence and DNA uptake
product
post-transcriptional regulator of comE expression
essential
no
synonyms
yrzD
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]

    • Gene

    Coordinates
    2,829,152 → 2,829,448

    The protein

    Catalyzed reaction/ biological activity

  • post-transcriptional control of ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' expression [Pubmed|19028902]
  • promotes the accumulation of its target ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' mRNA to septal and polar sites [Pubmed|22582279]
  • required for oriC placement during spore development [Pubmed|27059541]

    • [SW|Localization]

  • localizes to the division site and cell poles in a [protein|A8C0C2B7BCA6FFFF3811402D683FB7B99F7120A4|DivIVA] dependent fashion [Pubmed|22582279]

    • Expression and Regulation

    Operons

    genes
    [gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]-[gene|F0E7B6E000A5B06C9023C76F21551E754C8C45BA|secDF]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]
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    Biological materials

    Mutant

  • BKE27660 (Δ[gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAATTCCACGCTCCTTT, downstream forward: _UP4_TAGCAGGTTGATTCGCACAG
  • BKK27660 (Δ[gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAATTCCACGCTCCTTT, downstream forward: _UP4_TAGCAGGTTGATTCGCACAG

    • References

  • 19028902,22582279,27059541